MCL-1-BCL-2-IN-1-DataSheet-MedChemExpress

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摘要:Hotline:400-820-3792Inhibitors•Agonists•ScreeningLibrarieswww.MedChemExpress.cnMCL-1/BCL-2-IN-1Cat.No.:HY-129681分⼦式:C₃₁H₂₇BrN₂O₃S分⼦量:587.53作⽤靶点:Bcl-2Family作⽤通路:Apoptosis储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCOA.BIOLOGICALACTIVITY⽣物活性MCL-1/BCL-2-IN-2(CompoundNap-1)是⼀种有效的选择性Mcl-1和Bcl-2抑制剂，IC50分别为4.45和3.18μM[1]。IC50&TargetMcl-1Bcl-24.45μM(IC50)3.18μM(IC50)REFERENCES[1].WangZ,etal.ProteolysisTargetingChimerasfortheSelectiveDegradationofMcl-1/Bcl-2DerivedfromNonselectiveTargetBindingLigands.JMedChem.2019Sep12;62(17):8152-8163.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-589559951/1Fax:021-537003

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