Cdc7-IN-6-DataSheet-MedChemExpress

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摘要:Hotline:400-820-3792Inhibitors•Agonists•ScreeningLibrarieswww.MedChemExpress.cnCdc7-IN-6Cat.No.:HY-130518CASNo.:1402057-88-8分⼦式:C₂₁H₂₂F₃N₅O₄分⼦量:465.43作⽤靶点:CDK作⽤通路:CellCycle/DNADamage储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCOA.BIOLOGICALACTIVITY⽣物活性Cdc7-IN-6(compoundI-D)是⼀种有效的Cdc7激酶抑制剂(IC50=4nM)，具有抗肿瘤活性，详情请参考⽂献WO2019165473A1，compoundI-D。Cdc7是⼀种丝氨酸苏氨酸蛋⽩激酶酶，在细胞周期中对DNA复制的启动⾄关重要。体外研究Cdc7-IN-6demonstratespotentinhibitoryactivity(IC50[1].REFERENCES[1].ChristianAndrewHASSIG,etal.Methodsoftreatmentofcancercomprisingcdc7inhibitors.WO2019165473A1.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-589559951/1F

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